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Anti-summer Wear Jewelry Contact Dermatitis – Hc Network Jewelry Industry

Wear allergy care Jewelry The popular jewelry market, according to their ingredients, can generally be divided into two categories: one is pure gold with gold or platinum jewelry, the other is in Stainless steel Surface coated with a layer of material called ” Sulfuric acid Nickel “Material composed of ordinary metal jewelry. Dermatologists told reporters, wearing metal jewelry as contact dermatitis caused disease often known as jewelry. This is due to allergies contacts

To contain some of the jewelry in the metal, such as nickel, chromium, lead to allergic reactions. Some people allergic symptoms only manifested in the jewelry and skin contact areas, such as ears, neck, wrists, fingers, etc., and some people had systemic allergic reactions. First, skin irritation, and then beginning a small papules, blisters long and painful body itching. In general, patients with allergic reactions caused by jewelry uses only the outer skin of some drug treatment can cure. However, if inflammation of the skin are stimulated repeatedly, then prone to evil Venereal disease Change may lead to Cancer .

Nickel is a strong sensitization of the material, the silver-white hard metal, one of nickel oxide, nickel hydroxide is insoluble in water, and nickel nitrate, nickel sulfate is soluble in water, the ornaments contain soluble nickel sulfate water. Because people sweat more in summer, sweat in the water can cause a small amount of jewelry nickel sulfate solution surface, skin absorption allergic reaction.

Doctors to remind you that not all jewelry will be susceptible to an allergic reaction. Gold, silver or high-end Jade jewelry Jewelry is usually less likely to cause allergies, and some low-end simulation of decorative jewelry or chemically treated jade ornaments are likely to cause allergic reactions, therefore susceptible should avoid wearing gold, silver, chrome, Nickel And fake jade jewelry such as apt to cause dermatitis.

Not long to wear jewelry Summary

In addition, although Jewelry Beautiful and brilliant, can not wear day and night over many years, or may be Health Harm. Many women used to wear all year round Ring The result is a tight coupling ring finger skin, muscle, bone, into the circular depression deformity, affecting blood circulation, your fingers will become numb, acid swelling, pain, severe or even partial necrosis. Therefore should not be too tight to wear the ring, and activities should always take off your fingers. The girls are not off to sleep Earring Little do they know this is very easy to hook earrings on a metal ring or a hard object stab cheek.

Moreover, the long-term wear jewelry, the surrounding skin is difficult to clean. Particularly in the summer, a large number of human sweat, if you do not pay attention to sanitation, pathogenic microorganisms are likely to multiply in this breed, skin penetration, thus affecting their health.

Experts remind you to wear jewelry should always take off to clean. This will not only maintain the jewelry itself is clean as new, also very useful for the health of the wearer. Need to be reminded that there are many jewelry cleaning taboo Nongbu Hao jewelry itself will cause harm, the best professional cleaning staff invited to carry out maintenance.

“Jewelry disease” self-help approach

Be suffering from dermatitis jewelry how to do? Dermatologist’s advice is, first of all jewelry should be removed, remove the cause; followed the discretion to use 3% boric acid solution wet dressing, oven dry stone lotion applied externally or Fuqing Song, Yi Luosong other steroid steroid cream applied externally, while also under the guidance of a doctor taking cetirizine hydrochloride, Astemizole, a new music and other anti-sensitivity Organization Amine drugs.

But experts also advise, “Jewelry disease” although there evolved, but not a universal phenomenon, as long as the note on the line, do not cause panic, but no need to refuse to wear jewelry, because the market for sale of gold and silver jewelry After testing most of the relevant state departments, will not cause any harm to human health. As long as the time to buy is to big Shopping Or about the credibility of the shops and stores to buy will not go wrong. In addition, the wearing of jewelry not take too long, the best off to sleep at night. Have to keep jewelry clean is also important, do not sweat residue and other dirt. Comment Large In Small

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Eczema Drug Shows Promising Phase 2 Results for Treatment of Eosinophilic Esophagitis – AJMC.com Managed Markets Network

Eczema Drug Shows Promising Phase 2 Results for Treatment of Eosinophilic Esophagitis
AJMC.com Managed Markets Network
This new study suggests that dupilumab's ability to quickly reduce inflammation, which makes it so effective in clearing up atopic dermatitis (eczema), appears to be at work in reversing type 2 inflammation in eosinophilic esophagitis. Dupilumab works

eczema – Google News

Eczema Drug Shows Promising Phase 2 Results for Treatment of Eosinophilic Esophagitis – AJMC.com Managed Markets Network

Eczema Drug Shows Promising Phase 2 Results for Treatment of Eosinophilic Esophagitis
AJMC.com Managed Markets Network
This new study suggests that dupilumab's ability to quickly reduce inflammation, which makes it so effective in clearing up atopic dermatitis (eczema), appears to be at work in reversing type 2 inflammation in eosinophilic esophagitis. Dupilumab works

eczema – Google News

Black Children Miss Seeing Doctor for Eczema Despite Severe Effects – AJMC.com Managed Markets Network

Black Children Miss Seeing Doctor for Eczema Despite Severe Effects
AJMC.com Managed Markets Network
Researchers from Penn Medicine reported last week in the Journal of the American Academy of Dermatology that black children with eczema were 30% less likely to see a doctor for eczema than white children, based on an analysis of 12 years' worth of data …

eczema – Google News

Black Children Miss Seeing Doctor for Eczema Despite Severe Effects – AJMC.com Managed Markets Network

Black Children Miss Seeing Doctor for Eczema Despite Severe Effects
AJMC.com Managed Markets Network
Researchers from Penn Medicine reported last week in the Journal of the American Academy of Dermatology that black children with eczema were 30% less likely to see a doctor for eczema than white children, based on an analysis of 12 years' worth of data …

eczema – Google News

Probiotics Do Not Have a Significant Impact on Preventing Eczema, Asthma in Infants – AJMC.com Managed Markets Network

Probiotics Do Not Have a Significant Impact on Preventing Eczema, Asthma in Infants
AJMC.com Managed Markets Network
“One theory is that the absence of infectious exposure at a critical point in immune system development leads to a greater risk for eczema and asthma. Additionally, lack of key bacteria in the infant intestinal microbiota has been associated with the

eczema – Google News

Study Doubts the Association Between Eczema and Cardiovascular Disease – AJMC.com Managed Markets Network

Study Doubts the Association Between Eczema and Cardiovascular Disease
AJMC.com Managed Markets Network
Originally, Drucker created a hypothesis that suggested that people with atopic dermatitis (AD), a form of eczema, were more likely to have cardiovascular issues. However, the study revealed the absence of a link between AD and cardiovascular disease.

eczema – Google News

Three years in: what has the $42M Atopic Dermatitis Research Network produced?

In July it will be three years since the NIH awarded National Jewish Health in Denver, CO $ 31 million to create and administer the Atopic Dermatitis Research Network, a consortium of five academic sites across the US. A contractor, Rho Federal Systems of Chapel Hill, NC, won an $ 11 million contract to operate a center to coordinate statistics and clinical trials for the project.

That makes $ 42 million—spread over five years—which puts the project on the large end of NIH funding for individual biomedical efforts. The typical NIH research grant ranges from $ 100 thousand to $ 2 million, and anything bigger is fodder for university news releases. Which raises the question: what have US taxpayers gotten in return?

I ask this as a patient who is grateful that these scientists are working to understand a disease that affects me, my family, and millions in the US and worldwide.

The answer is not obvious, since the publications page on the ADRN website hasn’t been updated since July 2011.

According to the website:

The Atopic Dermatitis Research Network (ADRN) is a consortium of academic medical centers that will conduct clinical research studies in an attempt to learn more about skin infections associated with atopic dermatitis (AD). The studies will focus on antibiotic-resistant Staphylococcus aureus infections and widespread viral infections of the skin, both of which are more prevalent among AD patients. The ADRN will build on the work of the Atopic Dermatitis and Vaccinia Network (ADVN) which conducted clinical studies focused on making smallpox vaccinations safer for people with AD. 

This research will lead to a greater understanding of the immune system in AD patients and may lead to novel therapeutic strategies to manage or prevent infectious complications associated with this disease. 

The ADRN will conduct a number of clinical studies over the next five years and will be enrolling large numbers of people with AD.

A search on clinicaltrials.gov returns two entries for the ADRN: one (open) to create a database of patients for the study of genetic markers connected to susceptibility to infections, and one (completed) to look into how AD patients respond to a new flu vaccine.

The ADRN’s NIH contract number is HHSN272201000020C. A search in the NIH’s PubMed database returns 12 papers that acknowledge funding by that contract number. Three of those are review papers (which did not involve new research).

So that makes  two clinical trials and nine research papers, three years into a five-year $ 42 million project.

Should US taxpayers expect more; be satisfied; or be impressed?

The answer is probably that we will have to wait to find out.

In each year, a typical top university research lab operates on about $ 2-3M a year and publishes somewhere around ten papers. That’s roughly $ 200k a paper.

Three of the five years in the ADRN contract are up; three-fifths of $ 42M is around $ 24M. We might therefore naively estimate that we should have seen upwards of 100 papers produced so far.

Most likely the reasons there are only 12 at the moment are that you don’t start publishing papers right at the outset of a project. The research must be done first and then written up; and the process of getting accepted to a journal takes months. And the ADRN appears largely to rely on clinical trials–which take time to set up.

So why do we only see two trials listed on clinicaltrials.gov?

I’ve never had anything to do with a clinical trial, but when I was a researcher, I conducted animal experiments, and there were formidable administrative hurdles to get over before I could start work. I imagine that trials with human subjects are heavily regulated by the government, and for good reason. So the apparently small output of the ADRN to date is, I’m guessing, because it takes a long time to plan trials, get approval, and conduct them, before you can begin analyzing data and reporting it.

    Still, let’s keep in mind that the ADRN is an extension of the ADVN. It’s not like the ADRN began from scratch—the scientists had the momentum of existing expertise and administration and research aims.

    Looking at the titles of the published papers, I can’t immediately judge which are the most important. So I emailed Donald Leung, the principal investigator for the ADRN (he’s a professor and head of the Division of Pediatric Allergy and Immunology at National Jewish Health), and asked him whether he could summarize the consortium’s findings so far and highlight key points. I hope to hear back from him soon and perhaps to interview him on the phone.

    I’d like to know what ADRN scientists have found that surprises them. What have they learned that is truly new?

    And what is going to be truly useful to patients in the end? Publishing papers should not be the be-all and end-all of scientific research. What about patents? I’d like to know whether anyone in the ADRN has thought about controlling intellectual property and commercialization. While it’s true that clinical studies may highlight the ideal dosing amount or schedule for existing therapies, and this does not involve creating a new commercial enterprise, most medical technology must pass through the marketplace before it can benefit the consumer/patient.

    Someone has to do the dirty work of developing scientific discovery into therapy, and it’s not academic scientists.

    More to come.
    End Eczema

    New NEA post: Atopic Dermatitis Research Network needs trial participants

    This week you’ll find me blogging over at the National Eczema Association website. I interviewed Donald Leung of National Jewish Health about the Atopic Dermatitis Research Network. Three years in to a $ 42M program to investigate the links between genetics and our susceptibility to skin infections, the ADRN is registering patients with the NIH before proceeding with clinical trials.

    They still need black and Hispanic patients to sign up–eczema, genetics, and skin pathogens are different for different ethnic groups. The better your demographic is represented in the trials, the more that scientists will learn that applies to you.

    The ADRN has centers in Boston, Chicago, Denver, Los Angeles, Portland OR, and Rochester NY.

    If you’re interested in participating, email Judy Lairsmith at National Jewish or call 1-888-413-5852.
    End Eczema