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Researchers find common mutation in the genetics behind eczema
Medical Xpress The itchy, red and cracked skin typical of atopic dermatitis, otherwise known as eczema, is an inflammatory condition which affects up to one in five children, many of whom continue to suffer into adulthood. Topical corticosteroid creams and other … |
Tag Archives: Mutation
Gene mutation identified in atopic dermatitis
Gene mutation identified in atopic dermatitis
Gene mutation identified in atopic dermatitis
Eczema News – Gene Mutation Identified
Scientists from the National Institute of Allergy and Infectious Diseases (NIAID) have identified a gene mutation called CARD11 that led to atopic dermatitis/ eczema. Their findings were recently published in Nature Genetics (June 2017)1. Gene sequencing was performed for 8 individuals from 4 families, and the researchers found that although each family had a distinct mutation affecting a different region of the CARD11 protein, each mutation disrupted its normal function in T cells – an essential type of white blood cell.
The potential of this study was that glutamine may correct the defective signally mechanism of the mutated CARD11. Glutamine is available as a supplement, and the researches intend to study the effects of glutamine consumption on individuals with CARD11 mutations/ severe eczema. If the future study proved conclusive, it would open an easy therapeutics method for treating eczema!
