News-Medical.net |
New genetic mutations linked to eczema
Science Daily A genetic mutation could be the cause of severe eczema, according to new research published June 19 in Nature Genetics by researchers at the Uniformed Services University of the Health Sciences (USU). Researchers believe these new findings could … Researchers discover mutations in CARD11 gene that lead to eczema |
Tag Archives: Linked
New genetic mutations linked to eczema – Science Daily
News-Medical.net |
New genetic mutations linked to eczema
Science Daily A genetic mutation could be the cause of severe eczema, according to new research published June 19 in Nature Genetics by researchers at the Uniformed Services University of the Health Sciences (USU). Researchers believe these new findings could … Researchers discover mutations in CARD11 gene that lead to eczema |
New genetic mutations linked to eczema — ScienceDaily – Science Daily
News-Medical.net |
New genetic mutations linked to eczema — ScienceDaily
Science Daily A genetic mutation could be the cause of severe eczema, according to new research. Researchers believe these new findings could influence new treatment … Researchers discover mutations in CARD11 gene that lead to eczema |
Physical activity decreases inflammation linked to psoriatic arthritis
Inflammatory pain is a component of psoriatic arthritis, and participating in physical activity, such as yoga, is a way to reduce inflammation and manage chronic pain if a patient is experiencing it.
Modern medicine – Dermatology Times
Paraffin in skin creams linked to fire deaths
You may have read in the news this week (19 March 2017) about the link between people using paraffin based skin creams and dozens of fire deaths across England. People living with conditions such as eczema and psoriasis who use paraffin based creams and emollients may be at risk of setting themselves on fire.
It is worth emphasising that the use of the creams themselves for the treatment of skin conditions are not dangerous. The only becomes dangerous when mixed with other factors. An example of one of the deaths is Philip Hoe who died after accidentally setting himself on fire at Doncaster Royal Infirmary in 2006 when sparks from a cigarette reacted with the emollient cream he was covered in.
The Me
dicines and Health Care Products Regulatory Agency (MHRA) have issued warnings in the past, but only asked that a flammability warning should be on the packaging if a cream contained more than 50% paraffin. However, in light of the risks and because there have been 37 deaths linked with paraffin based creams since 2010, MHRA is now urging manufacturers to add a warning to the packaging of skin creams containing any level of paraffin.
More information on fire deaths related to the use of paraffin based creams.
Oxalic Acid Inflammation linked to Histamine, Thyroid Dysfunction & Hashimoto’s
I’ve spoken quite a bit about my experiences dealing with and the link between oxalic acid (found in some of the planet’s healthiest foods) and histamine related inflammation. Today it’s time to examine how a build up of oxalic acid found in low histamine foods like almonds, chard, potatoes, brown rice, millet and others, can not only exacerbate histamine inflammation, but also cause or contribute to thyroid dysfunction and Hashimoto’s. Both conditions are a huge and unfortunately seemingly quite common issue in our histamine intolerance and mast cell activation community.
Today’s post comes to you via something that popped up in my Facebook feed from the Thyroid Pharmacist Dr. Izabella Wentz. She began looking into the link when she noticed a number of her thyroid patients experiencing oxalic acid symptoms.
I’ve posted a great deal about the effects of oxalic acid found in plant foods: burning urination (in my case feeling like I’m peeing razor blades), needing to pee a lot, general symptoms of interstitial cystitis, pain during intercourse, kidney stones (I didn’t have stones though) and other troubles, and a general increase in histamine type inflammation.
The easiest way to explain how it works inflammation-wise is to use the bucket analogy: our body is a giant bucket and there’s only so much we can put in it before we spill over into symptoms. For example, if we’re exposed to pet dander, stress, intense exercise, heat or high histamine foods one by one, we may not spill over. Do them all in a day, or a week, and you may experience some uncomfortable inflammation symptoms. But it gets more annoying – let’s say you have too many salicylate rich foods, or histamine foods all at once, you may temporarily experience an inflammatory response (which is nearly identical to, or may actually be histamine related), even if you wouldn’t normally react to salicylate rich or oxalic acid foods. You can read more about all this in my post the Inflammation Bucket and Reacting to Everything? This May Be Why.
Dr. Wentz shared a study that found nearly eighty percent of adults autopsied had oxalate crystals in their thyroid glands. The older they were when they passed, the more likely the find became. A link to Hashimoto’s was made when it was realised that those with this autoimmune condition had a lower incidence of oxalate crystals, especially in their inflamed thyroid gland areas. The study authors concluded that oxalates could play a role in the disorder by causing inflammation that triggers the autoimmune response, resulting in the destruction of both the oxalate crystals and thyroid tissue.
According to Dr. Wentz, oxalate sensitivity should be suspected if you have these symptoms and a thyroid condition like Hashimoto’s or Graves.
Joint pain
General body pain
Burning urination
Burning stools
Symptoms of intestinal permeability (leaky gut)
Depression
Kidney stones
Your doctor can order a test for oxalate build up here.
I wasn’t living in a country where we could get any kind of oxalate testing so I just went ahead and did a modified low histamine diet combined with a low oxalate diet. You can read how I did it and find my food list for that particular adventure in my post The Low Oxalate Low Histamine Diet: The Missing Link?. Many of my more recent recipes like in the Man Food book are low oxalate and I have the Low Oxalate Cookbook which was my first foray into that world.
The best resource to find more information on the Hashimoto’s oxalate link seems to be Dr. Wentz’s website (that I’m aware of).
It’s finally here! Man Food – a high nutrient antihistamine and anti-inflammatory ingredient filled book geared towards guys, women who love to work out, yoga like they mean it, or just load up on healing nutrients. Features my personal shopping list of antihistamine and anti-inflammatory foods.
The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.
The Low Oxalate Cookbook features antihistamine and anti-inflammatory rich recipes.
Don’t miss the Low Histamine Beauty Survival Guide for non-toxic beauty tips, the skinny on histamine releasing (mast cell degranulating) beauty ingredients, antihistamine and anti-inflammatory beauty alternatives and the top brands natural brands I’ve found.
Take a peek at my other low histamine and antihistamine cookbooks for more high nutrient recipes
Fast Food Linked To Asthma And Eczema In Kids
AppId is over the quota AppId is over the quota Editor’s Choice
Academic Journal
Main Category: Nutrition / Diet
Also Included In: Eczema / Psoriasis;??Respiratory / Asthma;??Pediatrics / Children’s Health
Article Date: 15 Jan 2013 – 0:00 PDT Current ratings for:
Fast Food Linked To Asthma And Eczema In Kids 
Kids who eat fast food three or more times a week are likely to have more severe allergic asthma, rhinitis (hay fever), and eczema.
The finding came from new international research and was published in the journal Thorax.
Similarly, a previous study demonstrated that the benefits of breastfeeding in preventing asthma are cancelled out by eating fast food once or twice a week.
The results of the new study motivated the investigators to believe that a fast food diet may be playing a part in the increase in these conditions. If a causal relationship is found, it could have major importance to public health, considering how popular these fast food places are.
Over 319,000 thirteen to fourteen year olds from 51 countries and over 181,000 six to seven year olds from 31 countries were involved in the study. All of the subjects were enrolled in the International Study of Asthma and Allergies in Childhood (ISAAC), the largest of its kind involving over 100 countries and almost 2 million kids.
The teenagers and the parents of the kids were asked questions regarding symptoms of asthma (wheeze), eczema, rhinoconjunctivitis (runny or blocked nose along with itchy, watery eyes), and their diet on a weekly basis.
The severity of the symptoms that occurred over the past year were assessed through the questions, including how frequent they were and whether or not they interfered with daily routines or sleep patterns.http://www.eczemablog.net/
/ABS/Auto%20Blog%20Samurai/data/Eczema%20Blog/e/256px-Fast_food_%2528282678968%2529.jpg)
Regular fast food consumption raises the risk of asthma and eczema in children
They were also asked about their consumption of particular foods that were already associated with protective or damaging influences on health, including: fish meat veggies fruit bread pasta butter margarine rice pulses nuts milk eggs fast food/burgers Eating each of those foods was classified as never, occasionally, once or twice a week, or three or more times a week.
The experts controlled for variables that may have affected the results and found that the only type of food to have the same links across both age groups was fast food.
On analyzing their findings, the researchers proposed that “such consistency adds some weight to the possible causality of the relationship.”
Among all teens, consuming fast food was linked to current and severe symptoms of all 3 conditions, regardless of their gender, levels of affluence, or which country they were from.
Although the pattern among children was less convincing, there was still a link found between a fast food diet and symptoms except for current eczema, and poorer nations, except for present and severe asthma.
According to the authors, this dissimilarity may be due to the fact that kids have fewer choices when it comes to making food choices.
Three or more servings of fast food per week were associated with a 39% elevated risk of severe asthma among teens and a 27% increased chance among younger children, as well as to the severity of rhinitis and eczema, overall.
The experts discovered that fruit was protective in both age groups across all countries for all 3 conditions (current and severe) among kids, and among teens, for current and severe wheeze and rhinitis.
Consuming fruit 3 or more times per week was associated with a reduction in the severity of symptoms of 11% among teens and 14% among kids.
There are reasonable explanations for the results, the team pointed out. For example, high levels of saturated and trans fatty acids are found in fast food which can have an impact on immunity, while beneficial compounds and antioxidants are found in fruit.
The scientists stressed that this study did not demonstrate a cause and effect relationship, however, they said that more research is necessary.
The authors concluded:
“If the associations between fast foods and the symptom prevalence of asthma, rhinoconjunctivitis and eczema is causal, then the findings have major public health significance owing to the rising consumption of fast foods globally.”
Written by Sarah Glynn
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today
Philippa Ellwood, M Innes Asher, Luis Garcia-Marcos, Hywel Williams, Ulrich Keil, Colin Robertson, Gabriele Nagel, the ISAAC Phase III Study Group
THORAX 14 January 2013 doi:10.1136/thoraxjnl-2012-202285 Please use one of the following formats to cite this article in your essay, paper or report:
MLA
7 Apr. 2013.
Please note: If no author information is provided, the source is cited instead.
‘Fast Food Linked To Asthma And Eczema In Kids’
Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.
If you write about specific medications or operations, please do not name health care professionals by name.
All opinions are moderated before being included (to stop spam)
Contact Our News Editors
For any corrections of factual information, or to contact the editors please use our feedback form.
Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
View the original article here
Eczema Blog
Psoriasis Linked To Increased Risk Of Cardiovascular Disease By Mechanistic Discovery
AppId is over the quota AppId is over the quota Main Category: Eczema / Psoriasis
Also Included In: Cardiovascular / Cardiology
Article Date: 14 May 2012 – 0:00 PST Current ratings for:
Psoriasis Linked To Increased Risk Of Cardiovascular Disease By Mechanistic Discovery 
The link between psoriasis and cardiovascular events has been observed for years, however the mechanics were unknown. For the first time, Case Western Reserve University School of Medicine researchers have discovered preclinical evidence demonstrating that the inflammatory skin disease leads to cardiovascular disease. Further, the research demonstrated that aggressive reversal of psoriasis reduces the cardiovascular risk as well. Psoriasis is a chronic disease of the immune system that appears as raised, inflamed, scaly red patches of skin and is often associated with intense itch. In the United States, it affects between two and a half to six million patients. http://www.eczemablog.net/
Published in the Journal of Investigative Dermatology, the study used a new, innovative mouse model to demonstrate a causal connection between the skin disease and cardiovascular disease. Dr. Ward and her research team demonstrated that mice engineered to overexpress a protein called Tie-2 in the skin, develop a skin condition similar to human psoriasis. Using this model, they showed that persistent, chronic inflammation confined to the skin can result in inflammation in large arteries, such as the aorta.
“This discovery is paradigm shifting. There has been a link between the two diseases but to date we had not been able to show cause. Epidemiologic evidence from thousands of patients was convincing that psoriasis patients had a much greater chance of developing cardiovascular disease and dying from it,” says Nicole Ward, PhD, senior author of the study, assistant professor of dermatology and neurosciences at Case Western Reserve School of Medicine, and scientist with the Murdough Family Center for Psoriasis at University Hospitals Case Medical Center.
There is a known increased risk of heart, cerebrovascular, and peripheral artery diseases, as well as risk of death, in individuals suffering from a variety of chronic inflammatory diseases, such as rheumatoid arthritis (RA), colitis, gum disease, lupus, and psoriasis. Many researchers showed, statistically, that having psoriasis leads to an increased risk for cardiovascular disease and heart complications, however it was unclear why this occurs and it was challenging to separate out the significance of other lifestyle factors and their contributions to this risk, she adds.
Based on published clinical reports demonstrating psoriasis patients had increased risk of developing and dying of heart attack and stroke, Dr. Ward and her team set-out to investigate whether their mouse model of psoriasis would also show cardiac complications, mimicking these seen in human disease. They teamed up with experts in the role of inflammation in vessel injury – Yunmei Wang, PhD, assistant professor of medicine at the School of Medicine and Daniel I. Simon, MD the Herman K. Hellerstein Professor of Cardiovascular Research at the School of Medicine, and chief, Cardiovascular Medicine at University Hospitals Case Medical Center.
“We believed that chronic inflammation over a large area of the body may be the reason for an increased risk of cardiovascular complications in skin disease patients; however, until now we had no way to model and definitively prove this,” says Dr. Wang.
Dr. Ward and her team measured blood clot formation in the psoriasis mouse model and normal mice, revealing that time was greatly shortened in the diseased mice. This shortened time to vessel blockage is akin to a greater risk for blood vessel blockage in humans that leads to stroke or heart attack. Further examination revealed that mice with the skin disease also exhibited inflammation of the vessel wall similar to that observed with atherosclerotic lesions or plaques.
Importantly, and highly meaningful for patients with psoriasis, Dr. Ward’s work was able to demonstrate that upon reversal of the skin disease, the cardiovascular inflammation and blood clot formation were also decreased.
“Our observations of improved vessel wall inflammation and decreased clot formation following skin-specific repression of disease provide further evidence that skin inflammation promotes vascular inflammation and thrombosis and strongly suggests that aggressive treatment of skin disease may block pathways that produce cardiovascular disease in psoriasis patients,” says Dr. Ward.
Article adapted by Medical News Today from original press release. Click ‘references’ tab above for source.Visit our eczema / psoriasis section for the latest news on this subject. Dr. Ward presented these findings at the 2012 Society for Investigative Dermatology Annual Meeting in Raleigh, NC.
This research was funded by the National Institutes of Health, National Psoriasis Foundation, and the Murdough Family Center for Psoriasis.
Case Western Reserve University Please use one of the following formats to cite this article in your essay, paper or report:
MLA
7 Apr. 2013.
Please note: If no author information is provided, the source is cited instead.
‘Psoriasis Linked To Increased Risk Of Cardiovascular Disease By Mechanistic Discovery’
Please note that we publish your name, but we do not publish your email address. It is only used to let you know when your message is published. We do not use it for any other purpose. Please see our privacy policy for more information.
If you write about specific medications or operations, please do not name health care professionals by name.
All opinions are moderated before being included (to stop spam)
Contact Our News Editors
For any corrections of factual information, or to contact the editors please use our feedback form.
Please send any medical news or health news press releases to:
Note: Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional. For more information, please read our terms and conditions.
View the original article here
Eczema Blog