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Black children may suffer more severe eczema, but are less likely to receive treatment, study shows – Chicago Tribune


Chicago Tribune
Black children may suffer more severe eczema, but are less likely to receive treatment, study shows
Chicago Tribune
Black children may have more severe eczema than white children, but they are less likely to visit a doctor for this common inflammatory skin condition, new research shows. Eczema causes the skin to become red and itchy. Roughly 11 percent of children

eczema – Google News

Black children less likely to receive treatment for eczema despite increased severity – Healio

Black children less likely to receive treatment for eczema despite increased severity
Healio
Non-Hispanic black children are more likely to use ambulatory health care as well as to seek the care of a dermatologist for the treatment of eczema, according to findings published in the Journal of the American Academy of Dermatology. “Eczema might

eczema – Google News

Black Children Less Likely to See Doctor for Eczema Despite Being … – Newswise (press release)

Black Children Less Likely to See Doctor for Eczema Despite Being …
Newswise (press release)
A new study shows white children in America are more likely to see a doctor for treatment of eczema than black children, despite the fact that the disease is likely …

and more »

eczema – Google News

Black children less likely to see doctor for eczema despite being … – Medical Xpress


UPI.com
Black children less likely to see doctor for eczema despite being …
Medical Xpress
A new study shows white children in America are more likely to see a doctor for treatment of eczema than black children, despite the fact that the disease is likely …
Study finds black children less likely to see doctor for eczemaUPI.com

all 2 news articles »

eczema – Google News

Black children less likely to see doctor for eczema despite being more severely affected – Medical Xpress


UPI.com
Black children less likely to see doctor for eczema despite being more severely affected
Medical Xpress
A new study shows white children in America are more likely to see a doctor for treatment of eczema than black children, despite the fact that the disease is likely more severe among minorities. Research from the Perelman School of Medicine at the
Study finds black children less likely to see doctor for eczemaUPI.com

all 2 news articles »

eczema – Google News

Smokers twice as likely to develop debilitating skin disease

Tobacco smokers are twice as likely to develop a debilitating skin disease, according to new research published in the British Journal of Dermatology this week.

Hidradenitis suppurativa (HS) is a chronic and recurring inflammatory disease of the hair follicles, which causes a mixture of boil-like lumps, areas leaking pus, and scarring. It is estimated to affect around one per cent of the population, and it is difficult to predict the severity of individual cases and how they will respond to treatment.

The study was a retrospective cohort analysis, meaning that a database of medical records is examined to spot trends in a population’s health. The database that the researchers used has data on the health of over 50 million people in the United States, though for this study only patients with an active status in the database over the last three years who had race, gender, and age information, as well as at least one measurement for BMI with the study period were included. Patients who had already been diagnosed with HS before the start of the study were also excluded, as were patients who started smoking after they were diagnosed with HS.

Using this information the researchers were able to split the cohort into smokers and non-smokers and calculate the incidence of HS among both groups, taking into account other factors that influence HS incidence, such as age, gender, race, and obesity.

Of the 3,924,310 tobacco smokers, there were 7,860 patients diagnosed with HS during the study period, this compares to 8,430 cases of HS among 8,027,790 non-smokers. This equals an overall incidence among smokers of 0.20 per cent compared to 0.11 per cent among non-smokers.

Overall incidence was highest amongst the following smoking sub-groups: those aged 30-39 years (0.35 per cent); women (0.28 per cent); African Americans (0.46 per cent), and those with a BMI greater than, or equal to, 30 (0.33 per cent), qualifying them as obese.

Although the exact mechanisms linking tobacco smoking to HS are not understood, it has been speculated that nicotine has a role in triggering the disease.

Senior author, Dr Amit Garg, said: “This is the first population level evidence that tobacco smoking is a true risk factor for the development of Hidradenitis suppurativa. What is not yet understood is whether cessation of smoking can lead to improvement in disease activity.”

Matthew Gass of the British Association of Dermatologists said: “Hidradenitis suppurativa is a recurrent and painful disease, which can have an enormous physical and psychological impact on people, as such it is very important that medical professionals and patients understand the potential causes of this condition.

“This study also builds on the existing evidence base regarding the impact of smoking on skin health. There is already evidence that it is one of the biggest factors in skin ageing, and that it can increase the chances of acne scarring.”

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Negative food experiences make future histamine reactions more likely 

Conditioned taste aversion is a survival mechanism whereby animals learn to associate taste with a food that has made them sick; usually because it’s toxic or spoiled. In some cases the conditioned association between a food and sickness is so strong that the amygdala, the primitive part of the brain whose role it is to identify whether something is dangerous, can send the danger signal based on just the smell of a food alone. Sound familiar? Read on…references always at the bottom of post.

Chemotherapy has taught us a lot about taste aversion. Patients undergoing treatment who experience extreme nausea or sickness during it may develop a long term aversion to foods eaten during those months.

Granted, that’s an extreme example,  but some of us (myself included) have experienced years, if not decades of nausea (and worse) as a result of excess histamine or negative food reactions.

Histamine, dopamine, acetylcholine and serotonin are involved in the control of nausea and vomiting.

I stashed Motilium, a dopamine agonist that prevents nausea/vomiting in my handbag, by my bedside, and in my car for years. Really years. Took it pretty much every day.

As a kid I projectile vomited regularly. As an adult too really. Most memorably it’s happened while walking down the street, behind a curtain at a black tie function (while sober), and many others.

I think I may have, like chemotherapy patients, developed a conditioned taste aversion to foods (which triggered  major nausea every time I ate), or my inflammation bucket was so very full (read more about the bucket theory here) that it kept spilling over no matter what I ate.

So how does behavioural conditioning like taste aversion actually work?

Exciting research by scientists and those studying behaviour have shown that our beliefs affect the immune system. For example, they have found that placebos work (when they do) because people believe their doctor. They have faith that the medicine will heal them.

But a more exciting discovery was made in the last few years: that the immune system can be conditioned to  respond in a certain way by association with a subconscious stimulus. In her fascinating book CURE, investigative reporter Jo Malone interviews doctors and researchers at the cutting edge of the field of psychoneuroimmunolgy. They believe, and have proven, that behavioural conditioning can reproduce the effect of certain medications on the immune system, regardless of whether the patient believes it will heal them.

The scientists came up with variations on: giving an open placebo pill to patients (that’s there someone knows the pill is sugar/an inert substance), with a real medication, paired with a certain piece of music, and a liquid with an incongruous taste (ie a red drink that tastes like banana), at the same time in the same place. A few weeks and the medication would be reduced (or eliminated depending on the severity of the patient’s condition) but the rest would continue (music, drink, open placebo).
They found that the immune system continued to behave as it did when given the full dose of the real medication.

So despite the patient being fully aware that the medication was removed, their immune system had been conditioned to behave in a certain way.

Researchers have proven this in particular with asthmatics and measuring histamine released when the patients were stressed by believing they were being exposed to an allergen.

That’s how powerful conditioning can be.

That’s also how negative conditioning could be tripping us up.

If our immune system has been conditioned to respond to certain foods by releasing massive amounts of histamine, then this could keep going on even if the original issue has resolved.

Let’s say you were going through a time of immense stress, or eating while stressed at your desk always, or struggling to keep your cool with kids at your hem while cooking and eating, or had unpleasant family meal times, or were sick for a time, whatever, and your immune system came to associate stress with food and sickness.

That’s why when people ask me how I’ve managed to add so many foods back to my diet, including higher histamine ones, I attribute most of my gains to getting my diet right, but also fixing how my brain processes my body’s response to food and stress. I discuss my approach to healing this here and here.

It’s finally here! Man Food – a high nutrient antihistamine and anti-inflammatory ingredient filled book geared towards guys, women who love to work out, yoga like they mean it, or just load up on healing nutrients. Features my personal shopping list of antihistamine and anti-inflammatory foods.

The Anti-cookbook and all liquid Anti-Detox Book, don’t treat any conditions, but feature a plethora of the high nutrient antihistamine and anti-inflammatory ingredients that have been instrumental in helping me feed myself on a limited diet. The Anti-cookbook features a four page list of antihistamine and anti-inflammatory foods and comes in regular and Paleo.

—-REFERENCES—

“Conditioned taste aversion.” Wikipedia. Wikimedia Foundation, 21 May 2017. Web. 15 June 2017.

“Classical Conditioning (Pavlovian Conditioning).” SpringerReference (n.d.): n. pag. Web

Bernstein, Ilene L. “Conditioned food aversions as a consequence of cancer and its treatment.” PsycEXTRA Dataset (n.d.): n. pag. Web.

Bernstein, Ilene L. “Conditioned food aversions as a consequence of cancer and its treatment.” PsycEXTRA Dataset (n.d.): n. pag. Web.

“Domperidone.” Wikipedia. Wikimedia Foundation, 12 June 2017. Web. 15 June 2017.

Dark, Kathleen, Harman V. S. Peeke, George Ellman, and Mary Salfi. “Behaviorally Conditioned Histamine Release. Prior Stress and Conditionability and Extinction of the Response.” Annals of the New York Academy of Sciences 496.1 Neuroimmune I (1987): 578-82. Web.

“Chemoreceptor trigger zone.” Wikipedia. Wikimedia Foundation, 13 June 2017. Web. 15 June 2017.

Wager, Tor D., and Lauren Y. Atlas. “The neuroscience of placebo effects: connecting context, learning and health.” Nature Reviews Neuroscience 16.7 (2015): 403-18. Web.

talkhealth Blog

Psoriasis Patients Twice As Likely To Develop Diabetes

AppId is over the quota AppId is over the quota Editor’s Choice
Main Category: Eczema / Psoriasis
Also Included In: Diabetes;??Dermatology
Article Date: 16 Oct 2012 – 13:00 PST Current ratings for:
Psoriasis Patients Twice As Likely To Develop Diabetes
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A new meta-analysis of 27 studies shows a clear link between people with psoriasis and diabetes.


The study, led by UC Davis researchers, was published online in Archives of Dermatology, and found a strong association between the dry skin rash and blood sugar disorder.


Psoriasis is widespread skin condition that runs in families. It is characterized by red, raised, flaky and often itchy, rash, and is found mostly on the knees and elbows, but can appear anywhere. Doctors believe it is an autoimmune disease; the body thinks of the skin as foreign and therefore gives off an inflammatory response. Earlier studies have hinted that psoriasis could be a risk factor for diabetes.


April Armstrong, assistant professor of dermatology at UC Davis and lead investigator of this study, and her team examined 27 studies of patients with psoriasis. Five of these studies looked at how many of the patients developed diabetes during the period of study, 10 to 22 years. The remainder of the studies assessed the incidence of diabetes at the commencement of the study. In total, they examined over 314,000 people with psoriasis and compared them with 3.7 million people without the disease (a control group).


The collection of data for these studies shows that patients with mild psoriasis are more than 1.5 times more likely to develop diabetes than the general public, while those suffering from severe psoriasis are twice as likely.


Studies that assessed prevalence found patients with psoriasis had a 27 percent elevated risk of getting diabetes, compared with the general public.


All but one study found a link between psoriasis and diabetes. These trials contained data from outpatient clinics, insurance claims, and hospitals. The rate of diabetes was the same regardless of patients’ ethnicities or countries. Armstrong explains:


“The large sample size and consistent association between psoriasis and diabetes make these study findings very strong and suggest an underlying physiological link between the two diseases.”

The authors admit that additional research is needed to interpret how the two diseases are intertwined. Armstrong suggests changed immune pathways may be responsible for making psoriasis patients more vulnerable to diabetes.

She goes on to say:


“There is evidence that fat cells in psoriasis patients may not function normally. These cells secrete inflammatory substances known as cytokines that increase insulin resistance in the liver and muscle and initiate destruction of insulin-producing cells in the pancreas.”

More research can also verify other possible limiting factors that are seen in the current study; a factor that could be confusing, like concurrent medications used to treat psoriasis that may change the risk of developing diabetes.


It has been known that blood pressure is harder to control in patients with psoriasis and also that psoriasis patients suffer higher instances of heart attack, strokes, and cardiovascular-related deaths. In order to provide the best and earliest care, it is imperative for physicians to be aware of these predispositions.


Armstrong and her team plan to study endothelial cells, cells that line the blood vessels, in order to interpret the unseen physiological basis of psoriasis. They will soon create a network to share clinical data on patients with psoriasis.


Written by Kelly Fitzgerald
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Visit our eczema / psoriasis section for the latest news on this subject. “Psoriasis and the Risk of Diabetes Mellitus: A Systematic Review and Meta-analysis”
April W. Armstrong, MD, MPH; Caitlin T. Harskamp, BA; Ehrin J. Armstrong, MD, MSc
Archives of Dermatology, October 2012, doi:10.1001/2013.jamadermatol.406 Please use one of the following formats to cite this article in your essay, paper or report:

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Fitzgerald, Kelly. “Psoriasis Patients Twice As Likely To Develop Diabetes.” Medical News Today. MediLexicon, Intl., 16 Oct. 2012. Web.
7 Apr. 2013. APA

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